UMBRELLA (Unleashing a CoMprehensive, Holistic and Patient Centric Stroke Management for a Better, Rapid, AdvancEd and PersonaLised Stroke Diagnosis, TreAtment and Outcome Prediction) is a holistic approach to progress, reshape, and benchmark the overall stroke care pathway and set new and improved standards of care in terms of primary and secondary prevention, rapid access to treatments, early accurate diagnosis, stratification, management and real-time monitoring, therapeutic targets identification, and rehabilitation, recurrent stroke and related cardiovascular events. This innovative approach will transform healthcare systems by improving and harmonising professionals’ workflows in a more patient-centred, digitalised, and communicative manner.

The project will gather state-of-the-art technologies and data streamers across the whole stroke continuum to build, implement, and utilise an unprecedent real world federated data platform (U-Platform) for making available interoperable, harmonised and standardised longitudinal stroke real-world data, protocols, programs, and information across seven top-tier pan-European medical centres.

The U-platform would enable large development and training of artificial intelligence (AI) innovative tools through a novel Federated Learning infrastructure (FL-platform) that preserves data privacy and sovereignty.

UMBRELLA CONSORTIUM

UMBRELLA combines cross-cutting experts in clinical practice of stroke management by uniting seven top-tier hospitals from six European countries with proven competences in the validation of clinical tools in real life scenarios (VHIR, FPG, VUMC, EMC, KU Leuven, UKE, Unibas). Medical experts will be in close contact with data scientists versed in health data harmonisation and curation (EMC, NORA, EUT) and AI development (CERN, EUT).

Our role in this project

CERN will provide the design, development, deployment and operation of the UMBRELLA Federated Learning Platform based on CAFEIN.
Formulating criteria to evaluate and prioritise the project’s outcomes according to clinical potential, technology maturity, and unmet medical need;
Developing a comprehensive sustainability plan for the UMBRELLA U-, FL- and research platforms featuring a community of practice.